Recommended Readings: David Pellman, M.D. Friday June 1, 2018

Recommended Readings: David Pellman, M.D. Friday June 1, 2018

Friday Lectures

Friday, June 1, 2018  3:45 p.m.

Caspary Auditorium

David Pellman M.D.

Margaret M. Dyson Professor

Department of Cell Biology

Harvard Medical School

Mechanisms of Rapid Genome Evolution

Recommended Readings:

Science News

Dana-Farber Cancer Institute. Researchers identify origin of chromosomal oddity in some cancer cells. May 27, 2015. EurekAlert

Empirical Articles

Marteil, Gaelle; Guerrero, Adan; Vieira, Andre F.; et al. (2018). Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation. NATURE COMMUNICATIONS. 9    

Zhang, Cheng-Zhong; Spektor, Alexander; Cornils, Hauke; et al. (2015). Chromothripsis from DNA damage in micronuclei. NATURE. 522 (7555): 179-+

Selmecki, Anna M.; Maruvka, Yosef E.; Richmond, Phillip A.; et al. (2015). Polyploidy can drive rapid adaptation in yeast. NATURE. 519 (7543): 349-+

Crasta, Karen; Ganem, Neil J.; Dagher, Regina; et al. (2012). DNA breaks and chromosome pulverization from errors in mitosis. NATURE. 482 (7383): 53-U70

Carter, Scott L.; Cibulskis, Kristian; Helman, Elena; et al. (2012). Absolute quantification of somatic DNA alterations in human cancer. NATURE BIOTECHNOLOGY. 30 (5): 413-+

Ganem, Neil J.; Godinho, Susana A.; Pellman, David. (2009). A mechanism linking extra centrosomes to chromosomal instability. NATURE. 460 (7252): 278-U146

Review Paper

Zhang, Cheng-Zhong; Leibowitz, Mitchell L.; Pellman, David. (2013). Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements. GENES AND DEVELOPMENT. 27 (23): 2513-2530   

Gordon, David J.; Resio, Benjamin; Pellman, David. (2012). Causes and consequences of aneuploidy in cancer. NATURE REVIEWS GENETICS. 13 (3): 189-203

Book Chapter

Leibowitz, Mitchell L.; Zhang, Cheng-Zhong; Pellman, David. (2015). Chromothripsis: A New Mechanism for Rapid Karyotype Evolution. ANNUAL REVIEW OF GENETICS. 49: 183-211

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About the Author:

Ilaria Ceglia, Ph.D., Science Informationist - Ilaria joined the Markus Library Team in 2017. As science liaison between the Rockefeller scientific community and the library, Ilaria assists Rockefeller scientists find, and effectively use, the scholarly communication tools available at the library, provides customized literature searching, delivers research information reports and publications metric analysis to enhance collaborations between Rockefeller and leading scientific institutions, provides access to digital content to manage large data freely accessible. Ilaria manages a drug development database to perform clinical literature searches and drugs pipeline reports for Rockefeller research faculty, scientists and clinicians. As the NIH compliance monitor for the Rockefeller University, Ilaria helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to complement other resource center services, organize tutorial training sessions in areas of life sciences and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and PubMed literature searching, managing recommendation readings library blog for lectures and special seminars. Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New York, where she taught Cell Biology and Biochemistry. As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends and colleagues.

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