Friday Lecture Series via Zoom webinars
Friday, April 17, 2020 3:45 p.m
Ralph S. Baric, Ph.D.
William R. Kenan, Jr. Distinguished Professor
Department of Epidemiology, Microbiology and Immunology
University of North Carolina
Epidemic and Pandemic Coronaviruses
Recommended Readings:
Science News
Antiviral Against COVID-19 Reduces Damage in Mouse Lungs. April 7, 2020. Technology Networks
Empirical Articles
Wan, Yushun; Shang, Jian; Graham, Rachel; et al. (2020). Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus. JOURNAL OF VIROLOGY. 94 (7)
Menachery, Vineet D.; Dinnon, Kenneth H., III; Yount, Boyd L., Jr.; et al. (2020). Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection. JOURNAL OF VIROLOGY. 94 (5)
Sheahan TP; Sims AC; Leist SR; Schäfer A; et al. (2020). Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. NATURE COMMUNICATION. 11 (1): 222
Graham, Jessica B.; Swarts, Jessica L.; Menachery, Vineet D.; et al. (2020). Immune Predictors of Mortality After Ribonucleic Acid Virus Infection. JOURNAL OF INFECTIOUS DISEASES. 221 (6): 882-889
Wahl, Angela; De, Chandrav; Fernandez, Maria Abad; et al. (2019). Precision mouse models with expanded tropism for human pathogens. NATURE BIOTECHNOLOGY. 37 (10): 1163
Menachery, Vineet D.; Gralinski, Lisa E.; Mitchell, Hugh D.; et al. (2018). Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines. JOURNAL OF VIROLOGY. 92 (17)
Sheahan, Timothy P. and Baric, Ralph S. (2018). Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics? FUTURE VIROLOGY. 13 (3): 143-146
Tang, Xian-Chun; Agnihothram, Sudhakar S.; Jiao, Yongjun; et al. (2014). Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution. PNAS. 111 (19): E2018-E2026
Eckerle, Lance D.; Becker, Michelle M.; Halpin, Rebecca A.; et al. (2010). Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing. PLOS PATHOGENS. 6 (5)
Review Papers
Graham, Rachel L.; Donaldson, Eric F.; Baric, Ralph S. (2013). A decade after SARS: strategies for controlling emerging coronaviruses. NATURE REVIEWS MICROBIOLOGY. 11 (12): 836-848
Graham, Rachel L.; Baric, Ralph S. (2010). Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission. JOURNAL OF VIROLOGY. 84 (7): 3134-3146
Book Chapters
Cockrell, Adam S.; Beall, Anne; Yount, Boyd; et al. (2017). Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses. REVERSE GENETICS OF RNA VIRUSES: METHODS AND PROTOCOLS. 1602: 59-81
Peck, Kayla M.; Burch, Christina L.; Heise, Mark T.; et al. (2015). Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary Perspectives. ANNUAL REVIEW OF VIROLOGY. 2: 95-117