Other Lectures
Monday, April 27, 2020 4:00 p.m.
Carson Family Auditorium
Ulrich F. Hartl, M.D., Ph.D.
Professor and Director
Department of Cellular Biochemistry
Max Planck Institute
Molecular chaperone functions in protein folding and proteome surveillance
Recommended Readings:
Empirical Articles
Jayaraj, Gopal G.; Hipp, Mark S.; Hartl, F. Ulrich. (2020). Functional Modules of the Proteostasis Network. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 12 (1)
Su, Ting; Izawa, Toshiaki; Thoms, Matthias; et al. (2019). Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. NATURE. 570 (7762): 538-+
Vincenz-Donnelly, Lisa; Holthusen, Hauke; Koerner, Roman; et al. (2018). High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. EMBO JOURNAL Volume. 37 (3): 337-350
Hartl, F. Ulrich (2017). Unfolding the chaperone story. MOLECULAR BIOLOGY OF THE CELL. 28 (22): 2919-2923
Walther, Dirk M.; Kasturi, Prasad; Zheng, Min; et al. (2015). Widespread Proteome Remodeling and Aggregation in Aging C-elegans. CELL. 161 (4): 919-932
Dou, F; Netzer, WJ; Tanemura, K; et al. (2003). Chaperones increase association of tau protein with microtubules. PNAS. 100 (2): 721-726
Review Papers
Hipp, Mark S.; Kasturi, Prasad; Hartl, F. Ulrich. (2019). The proteostasis network and its decline in ageing. NATURE REVIEWS MOLECULAR CELL BIOLOGY. 20 (7): 421-435
Hartl, F. Ulrich; Bracher, Andreas; Hayer-Hartl, Manajit. (2011). Molecular chaperones in protein folding and proteostasis. NATURE. 475 (7356): 324-332
Book Chapters
Hartl, F. Ulrich (2017). Protein Misfolding Diseases. ANNUAL REVIEW OF BIOCHEMISTRY. 86: 21-26
Kim, Yujin E.; Hipp, Mark S.; Bracher, Andreas; et al. (2013). Molecular Chaperone Functions in Protein Folding and Proteostasis. ANNUAL REVIEW OF BIOCHEMISTRY. 82: 323-355