Friday Lectures
Friday, September 20, 2019 3:45 p.m
Caspary Auditorium
Gina G. Turrigiano Ph.D.
Joseph Levitan Professor of Vision Science
Department of Biology
Brandeis University
Firing Rate Homeostasis in Neocortical Networks
Recommended Readings:
Empirical Articles
Miska, Nathaniel J.; Richter, Leonidas M. A.; Cary, Brian A.; et al. (2018). Sensory experience inversely regulates feedforward and feedback excitation-inhibition ratio in rodent visual cortex. ELIFE. 7
Hengen, Keith B.; Pacheco, Alejandro Torrado; McGregor, James N.; et al. (2016). Neuronal Firing Rate Homeostasis Is Inhibited by Sleep and Promoted by Wake. CELL. 165 (1): 180-191
Gainey, Melanie A.; Tatavarty, Vedakumar; Nahmani, Marc; et al. (2015). Activity-dependent synaptic GRIP1 accumulation drives synaptic scaling up in response to action potential blockade. PNAS. 112 (27): E3590-E3599
Nahmani, Marc; Turrigiano, Gina G. (2014). Deprivation-Induced Strengthening of Presynaptic and Postsynaptic Inhibitory Transmission in Layer 4 of Visual Cortex during the Critical Period. JOURNAL OF NEUROSCIENCE. 34 (7): 2571-2582
Hengen, Keith B.; Lambo, Mary E.; Van Hooser, Stephen D.; et al. (2013). Firing Rate Homeostasis in Visual Cortex of Freely Behaving Rodents. NEURON. 80 (2): 335-342
Turrigiano, Gina. (2012). Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 4 (1)
Review Papers
Keck, Tara; Toyoizumi, Taro; Chen, Lu; et al. (2017). Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 372 (1715)
Turrigiano, Gina G. (2008). The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses. CELL. 135 (3): 422-435
Turrigiano, Gina. (2007). Homeostatic signaling: the positive side of negative feedback. CURRENT OPINION IN NEUROBIOLOGY. 17 (3): 318-324
Book Chapter
Turrigiano, Gina. (2011). Too Many Cooks? Intrinsic and Synaptic Homeostatic Mechanisms in Cortical Circuit Refinement. ANNUAL REVIEW OF NEUROSCIENCE. 34: 89-103