Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, March 9, 2026
Nathaniel Heintz, Ph.D.
James and Marilyn Simons Professor, Director, Fischer Center for Alzheimer’s Research and Head of the Laboratory of Molecular Biology, The Rockefeller University; Investigator, Howard Hughes Medical Institute
Molecular Insights into the Pathogenesis and Treatment of Huntington’s and Alzheimer’s Diseases
Recommended Readings:
McLellan, Rio, et al. “When the Brain’s Switchboard Short Circuits: Cell‐Type Specific Molecular Characterization of the Human Thalamus in Alzheimer’s Disease.” Alzheimer’s & Dementia 21 (2025): e105194.
Baffuto, Matthew, et al. “Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington’s disease.” bioRxiv (2025).
Mätlik, Kert, Christina Pressl, and Nathaniel Heintz. “Cell Type–Specific Studies of Human Tissue for Investigation of the Molecular Cell Biology of Late-Onset Neurodegenerative Disease.” Annual Review of Neuroscience 48 (2025).
Pressl, Christina, et al. “Isolation and molecular profiling of nuclei of specific neuronal types from human cerebral cortex and striatum.” Current Protocols 4.12 (2024): e70067.
Roussarie, Jean-Pierre, et al. “Selective neuronal vulnerability in Alzheimer’s disease: a network-based analysis.” Neuron 107.5 (2020): 821-835.