Recommended Readings: David Baker, Ph.D. Friday January 11, 2019

Recommended Readings: David Baker, Ph.D. Friday January 11, 2019

 

David Baker Ph.D.

Friday Lectures

Friday, January 11, 2018  3:45 p.m

Caspary Auditorium

David Baker Ph.D.

Professor of Biochemistry and Director of the Institute for Protein Design

University of Washington

The Coming of Age of De Novo Protein Design

Recommended Readings:

Science News

Scientists program proteins to pair exactly. December 19, 2018. Science Daily

Empirical Articles

Shen, Hao; Fallas, Jorge A.; Lynch, Eric; et al. (2018). De novo design of self-assembling helical protein filaments. SCIENCE. 362 (6415): 705-709

Marcos, Enrique; Chidyausiku, Tamuka M.; McShan, Andrew C.; et al. (2018). De novo design of a non-local beta-sheet protein with high stability and accuracy. NATURE STRUCTURAL AND MOLECULAR BIOLOGY. 25 (11): 1028-1030

Dou, Jiayi; Vorobieva, Anastassia A.; Sheffler, William; et al. (2018). De novo design of a fluorescence-activating beta-barrel. NATURE. 561 (7724): 485-+

Lu, Peilong; Min, Duyoung; DiMaio, Frank; et al. (2018). Accurate computational design of multipass transmembrane proteins. SCIENCE. 359 (6379): 1042-1046

Hosseinzadeh, Parisa; Bhardwaj, Gaurav; Mulligan, Vikram Khipple; et al. (2017). Comprehensive computational design of ordered peptide macrocycles. SCIENCE. 358 (6369): 1461-1466

Review Paper

Huang, Po-Ssu; Boyken, Scott E.; Baker, David. (2016). The coming of age of de novo protein design. NATURE. 537 (7620): 320-327

Fleishman, Sarel J.; Baker, David. (2012). Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution. CELL. 149 (2): 262-273

Book Chapter

Thyme, Summer; Baker, David. (2014). Redesigning the Specificity of Protein-DNA Interactions with Rosetta. HOMING ENDONUCLEASES: METHODS AND PROTOCOLS. 1123: 265-282

Whitehead, Timothy A.; Baker, David; Fleishman, Sarel J. (2013). Computational Design of Novel Protein Binders and Experimental Affinity Maturation. METHODS IN PROTEIN DESIGN. 523: 1-19

 Leaver-Fay, Andrew; Tyka, Michael; Lewis, Steven M.; et al. (2011). Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules. METHODS IN ENZYMOLOGY. 487: 545-574

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About the Author:

Ilaria Ceglia, Ph.D., Science Informationist - Ilaria joined the Markus Library Team in 2017. As science liaison between the Rockefeller scientific community and the library, Ilaria assists Rockefeller scientists find, and effectively use, the scholarly communication tools available at the library, provides customized literature searching, delivers research information reports and publications metric analysis to enhance collaborations between Rockefeller and leading scientific institutions, provides access to digital content to manage large data freely accessible. Ilaria manages a drug development database to perform clinical literature searches and drugs pipeline reports for Rockefeller research faculty, scientists and clinicians. As the NIH compliance monitor for the Rockefeller University, Ilaria helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to complement other resource center services, organize tutorial training sessions in areas of life sciences and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and PubMed literature searching, managing recommendation readings library blog for lectures and special seminars. Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New York, where she taught Cell Biology and Biochemistry. As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends and colleagues.