Friday Lectures
Friday, January 17, 2020 3:45 p.m
Caspary Auditorium
Patrick Cramer, Ph.D.
Director
Department of Molecular Biology
Max Planck Institute
Mechanisms of Chromatin Transcription
Recommended Readings:
Empirical Articles
Farnung, Lucas; Vos, Seychelle M.; Cramer, Patrick. (2018). Structure of transcribing RNA polymerase II-nucleosome complex. NATURE COMMUNICATIONS. 9
Boehning, Marc; Dugast-Darzacq, Claire; Rankovic, Marija; et al. (2018). RNA polymerase II clustering through carboxy-terminal domain phase separation. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 25 (9): 833-+
Vos, Seychelle M.; Farnung, Lucas; Urlaub, Henning; et al. (2018). Structure of paused transcription complex Pol II-DSIF-NELF. NATURE. 560 (7720): 601-+
Vos, Seychelle M.; Farnung, Lucas; Boehning, Marc; et al. (2018). Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. NATURE. 560 (7720): 607-+
Nozawa, Kayo; Schneider, Thomas R.; Cramer, Patrick. (2017). Core Mediator structure at 3.4 angstrom extends model of transcription initiation complex. NATURE. 545 (7653): 248-+
Farnung, Lucas; Vos, Seychelle M.; Wigge, Christoph; et al. (2017). Nucleosome-Chd1 structure and implications for chromatin remodeling. NATURE. 550 (7677): 539-+
Gressel, Saskia; Schwalb, Bjorn; Decker, Tim Michael; et al. (2017). CDK9-dependent RNA polymerase II pausing controls transcription initiation. ELIFE. 6
Plaschka, Clemens; Nozawa, Kayo; Cramer, Patrick. (2016). Mediator Architecture and RNA Polymerase II Interaction. JOURNAL OF MOLECULAR BIOLOGY. 428 (12): 2569-2574
Schwalb, Bjorn; Michel, Margaux; Zacher, Benedikt; et al. (2016). TT-seq maps the human transient transcriptome. SCIENCE. 352 (6290): 1225-1228
Review Paper
Vannini, Alessandro; Cramer, Patrick. (2012). Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries. MOLECULAR CELL. 45 (4): 439-446
Book Chapter
Engel, Christoph; Neyer, Simon; Cramer, Patrick. (2018). Distinct Mechanisms of Transcription Initiation by RNA Polymerases I and II. ANNUAL REVIEW OF BIOPHYSICS. 47: 425-446