Friday Lecture Series
(open to the Rockefeller community)
Friday, November 4, 2022
Agata Smogorzewska, M.D., Ph.D.
Associate Professor,
Head of the Laboratory of Genome Maintenance,
The Rockefeller University
When Watson and Crick Get Linked: DNA Interstrand Crosslink Repair and Human Disease
Recommended Readings:
Empirical Articles
Jung, M., Ilyashov, I., Park, Y., Donovan, F. X., Ramanagoudr-Bhojappa, R., Keahi, D., Durmaz, J. A., Choijilsuren, H. B., Goldfarb, A., Stein, M., Kim, J., White, R. R., Sridhar, S., Noonan, R., Wiley, T., Carroll, T. S., Lach, F. P., Auerbach, A. D., Miranda, I., Chandrasekharappa, S. C., & Smogorzewska, A. (2022). ALDH9A1 Deficiency as a Source of Endogenous DNA Damage that Requires Repair by the Fanconi Anemia Pathway. bioRxiv
Webster, A. L. H., Sanders, M. A., Patel, K., Dietrich, R., Noonan, R. J., Lach, F. P., White, R. R., Goldfarb, A., Hadi, K., Edwards, M. M., Donovan, F. X., Jung, M., Sridhar, S., Fedrigo, O., Tian, H., Rosiene, J., Heineman, T., Kennedy, J. A., Bean, L., Rosti, O., Tryon, R., Gonzalez, A.-M., Rosenberg, A., Luo, J.-D., Carrol, T., Velleuer, E., Rastatter, J. C., Wells, S. I., Surrallés, J., Bagby, G., MacMillan, M. L., Wagner, J. E., Cancio, M., Boulad, F., Scognamiglio, T., Vaughan, R., Koren, A., Imielinski, M., Chandrasekharappa, S., Auerbach, A. D., Singh, B., Kutler, D. I., Campbell, P. J., & Smogorzewska, A. (2021). Fanconi Anemia Pathway Deficiency Drives Copy Number Variation in Squamous Cell Carcinomas. bioRxiv
Elango, R., Panday, A., Lach, F. P., Willis, N. A., Nicholson, K., Duffey, E. E., Smogorzewska, A., & Scully, R. (2022). The structure-specific endonuclease complex SLX4-XPF regulates Tus-Ter-induced homologous recombination. Nature structural & molecular biology, 29(8), 801–812.
Caballero, M., Ge, T., Rebelo, A. R., Seo, S., Kim, S., Brooks, K., Zuccaro, M., Kanagaraj, R., Vershkov, D., Kim, D., Smogorzewska, A., Smolka, M., Benvenisty, N., West, S. C., Egli, D., Mace, E. M., & Koren, A. (2022). Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Human molecular genetics, 31(17), 2899–2917.
Yang, Z., Wu, X. S., Wei, Y., Polyanskaya, S. A., Iyer, S. V., Jung, M., Lach, F. P., Adelman, E. R., Klingbeil, O., Milazzo, J. P., Kramer, M., Demerdash, O. E., Chang, K., Goodwin, S., Hodges, E., McCombie, W. R., Figueroa, M. E., Smogorzewska, A., & Vakoc, C. R. (2021). Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia. Cancer discovery, 11(9), 2300–2315.
