Friday Lecture Series
(open to the Rockefeller community)
Friday, March 25, 2022
Geeta Narlikar, Ph.D.
Professor,
Department of Biochemistry and Biophysics
Co-director Tetrad Graduate Program,
UCSF
Genome Regulation by ATP-dependent Chromatin Remodeling and Phase-separation
Recommended Readings:
Empirical Articles
Gamarra, N., & Narlikar, G. J. (2021). Histone dynamics play a critical role in SNF2h-mediated nucleosome sliding. Nature structural & molecular biology, 28(7), 548–551.
Keenen, M. M., Brown, D., Brennan, L. D., Renger, R., Khoo, H., Carlson, C. R., Huang, B., Grill, S. W., Narlikar, G. J., & Redding, S. (2021). HP1 proteins compact DNA into mechanically and positionally stable phase separated domains. eLife, 10, e64563.
Abdulhay, N. J., McNally, C. P., Hsieh, L. J., Kasinathan, S., Keith, A., Estes, L. S., Karimzadeh, M., Underwood, J. G., Goodarzi, H., Narlikar, G. J., & Ramani, V. (2020). Massively multiplex single-molecule oligonucleosome footprinting. eLife, 9, e59404.
Dumesic, P. A., Stoddard, C. I., Catania, S., Narlikar, G. J., & Madhani, H. D. (2020). ATP Hydrolysis by the SNF2 Domain of Dnmt5 Is Coupled to Both Specific Recognition and Modification of Hemimethylated DNA. Molecular cell, 79(1), 127–139.e4.
Srinivasan, R., Nady, N., Arora, N., Hsieh, L. J., Swigut, T., Narlikar, G. J., Wossidlo, M., & Wysocka, J. (2020). Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage. Science advances, 6(12), eaaz9115.
