Webinar Monday Lecture Series
(open to the Rockefeller community)
Monday, April 26, 2021
Ekaterina V. Vinogradova, Ph.D.
Assistant Professor and Head
Laboratory of Chemical Immunology and Proteomics
The Rockefeller University
Chemical Proteomic Approaches to Study Immunology and Neuroinflammation
Recommended Readings:
Empirical Articles
Kuljanin, Miljan; Mitchell, Dylan C.; Schweppe, Devin K.; et al. (2021). Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. NATURE BIOTECHNOLOGY
Vinogradova, Ekaterina V.; Zhang, Xiaoyu; Remillard, David; et al. (2020). An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. CELL. 182 (4): 1009-1026.e29
Zambaldo, Claudio; Vinogradova, Ekaterina V.; Qi, Xiaotian; et al. (2020). 2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 142 (19): 8972-8979
Yamashita, Yu; Vinogradova, Ekaterina V.; Zhang, Xiaoyu; et al. (2020). A Chemical Proteomic Probe for the Mitochondrial Pyruvate Carrier Complex. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 59 (10): 3896-3899
Yamashita, Yu; Vinogradova, Ekaterina V.; Zhang, Xiaoyu; et al. (2020). A Chemical Proteomic Probe for the Mitochondrial Pyruvate Carrier Complex. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 59 (10): 3896-3899
Senkane, Kristine; Vinogradova, Ekaterina V.; Suciu, Radu M.; et al. (2019). The Proteome-Wide Potential for Reversible Covalency at Cysteine. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 58 (33): 11385-11389
Bar-Peled, Liron; Kemper, Esther K.; Suciu, Radu M.; et al. (2017). Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. CELL. 171 (3): 696-709
Vinogradova, Ekaterina V.; Zhang, Chi; Spokoyny, Alexander M.; et al. (2015). Organometallic palladium reagents for cysteine bioconjugation. NATURE. 526 (7575): 687-691
Review Paper
Vinogradova, Ekaterina V. (2017). Organometallic chemical biology: an organometallic approach to bioconjugation. PURE AND APPLIED CHEMISTRY. 89 (11): 1619-1640