Recommended Readings: Job Dekker, Ph.D. Friday February 5, 2021

Recommended Readings: Job Dekker, Ph.D. Friday February 5, 2021

Webinar Friday Lecture SeriesJob Dekker, Ph.D.

(open to the Tri-I community)

Friday, February 5, 2021

Job Dekker, Ph.D.

Joseph J. Byrne Chair, Professor and Co-director

Department of Biochemistry and Molecular Pharmacology

University of Massachusetts Medical School

Mechanisms of Chromosome Folding


Recommended Readings:

Empirical Articles

Fitz-James, Maximilian H.; Tong, Pin; Pidoux, Alison L.; et al. (2020). Large domains of heterochromatin direct the formation of short mitotic chromosome loops. ELIFE. 9

Abramo, Kristin; Valton, Anne-Laure; Venev, Sergey V.; et al. (2019). A chromosome folding intermediate at the condensin-to-cohesin transition during telophase. NATURE CELL BIOLOGY. 21 (11): 1393-

Gibcus, Johan H.; Samejima, Kumiko; Goloborodko, Anton; et al. (2018). A pathway for mitotic chromosome formation. SCIENCE. 359 (6376): 652-

Schalbetter, Stephanie Andrea; Goloborodko, Anton; Fudenberg, Geoffrey; et al. (2017). SMC complexes differentially compact mitotic chromosomes according to genomic context. NATURE CELL BIOLOGY. 19 (9): 1071-

Crane, Emily; Bian, Qian; McCord, Rachel Patton; et al. (2015). Condensin-driven remodelling of X chromosome topology during dosage compensation. NATURE. 523 (7559): 240-U299

Review Papers

Oomen, Marlies E.; Dekker, Job. (2017). Epigenetic characteristics of the mitotic chromosome in 1D and 3D. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. 52 (2): 185-204

Dekker, Job; Heard, Edith. (2015). Structural and functional diversity of Topologically Associating Domains. FEBS LETTERS. 589 (20): 2877-2884

Dekker, Job. (2014). Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture. EPIGENETICS & CHROMATIN. 7

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About the Author:

Ilaria Ceglia, Ph.D., Science Informationist - Ilaria joined the Markus Library Team in 2017. As science liaison between the Rockefeller scientific community and the library, Ilaria assists Rockefeller scientists find, and effectively use, the scholarly communication tools available at the library, provides customized literature searching, delivers research information reports and publications metric analysis to enhance collaborations between Rockefeller and leading scientific institutions, provides access to digital content to manage large data freely accessible. Ilaria manages a drug development database to perform clinical literature searches and drugs pipeline reports for Rockefeller research faculty, scientists and clinicians. As the NIH compliance monitor for the Rockefeller University, Ilaria helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to complement other resource center services, organize tutorial training sessions in areas of life sciences and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and PubMed literature searching, managing recommendation readings library blog for lectures and special seminars. Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New York, where she taught Cell Biology and Biochemistry. As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends and colleagues.