Webinar Monday Lecture Series
(open to the Rockefeller community)
Monday, December 14, 2020
Gregory M. Alushin, Ph.D.
Assistant Professor and Head
Laboratory of Structural Biophysics and Mechanobiology
The Rockefeller University
Visualizing mechanisms of cellular force-sensing
Recommended Readings:
Empirical Articles
Mei, Lin; de los Reyes, Santiago Espinosa; Reynolds, Matthew J.; et al. (2020). Molecular mechanism for direct actin force-sensing by alpha-catenin. ELIFE. 9
Sarker, Muzaddid; Lee, Hyunna T.; Mei, Lin; et al. (2019). Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. JOURNAL OF MOLECULAR BIOLOGY. 431 (8): 1604-1618
Ti, Shih-Chieh; Alushin, Gregory M.; Kapoortv, Tarun M. (2018). Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability. DEVELOPMENTAL CELL. 47 (2): 175-190
Omabegho T, Gurel PS, Cheng CY, Kim LY, Ruijgrok PV, Das R, Alushin GM, Bryant Z. (2018). Controllable molecular motors engineered from myosin and RNA. NATURE NANOTECHNOLOGY. 13 (1): 34-40
Gural, Pinar S.; Kim, Laura Y.; Rujigrok, Paul V.; et al. (2017). Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity. ELIFE. 6
Kim, Laura Y.; Thompson, Peter M.; Lee, Hyunna T.; et al. (2016). The Structural Basis of Actin Organization by Vinculin and Metavinculin. JOURNAL OF MOLECULAR BIOLOGY. 428 (1): 10-25