Recommended Readings: Agata Smogorzewska, M.D., Ph.D. Monday December 16, 2019

Recommended Readings: Agata Smogorzewska, M.D., Ph.D. Monday December 16, 2019

Monday Lectures Agata Smogorzewska, M.D.,Ph.D.

Monday, December 16, 2019  4:00 p.m.

Carson Family Auditorium

Agata Smogorzewska, M.D., Ph.D.

Associate Professor and Head

Laboratory of Genome Maintenance

The Rockefeller University

Stress Response at the Replication Fork


Recommended Readings:

Empirical Articles

Rickman, K.A., Noonan, R., Lach, F.P., Sridhar, S., Wang, A.T., Abhyankar, A., Kelly, M., Auerbach, A.D., and Smogorzewska, A. (2019). Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand crosslinks. bioRxiv, 811968

Kottemann, Molly C.; Conti, Brooke A.; Lach, Francis P.; et al. (2018). Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity. MOLECULAR CELL. 69 (1): 24-35.e5

Thongthip S, Conti BA, Lach FP, Smogorzewska A. (2017). Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells. bioRxiv 151472

Wang, Anderson T.; Kim, Taeho; Wagner, John E.; et al. (2015). A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination. MOLECULAR CELL. 59 (3): 478-490

Joo, Woo; Xu, Guozhou; Persky, Nicole S.; et al. (2011). Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway. SCIENCE. 333 (6040): 312-316

Kim, Yonghwan; Lach, Francis P.; Desetty, Rohini; et al. (2011). Mutations of the SLX4 gene in Fanconi anemia. NATURE GENETICS. 43 (2): 142-U91

Svendsen, Jennifer M.; Smogorzewska, Agata; Sowa, Mathew E.; et al. (2009). Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair. CELL. 138 (1): 63-77

Ishiai, Masamichi; Kitao, Hiroyuki; Smogorzewska, Agata; et al. (2008). FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 15 (11): 1138-1146

Review Papers

Rickman, Kimberly; Smogorzewska, Agata. (2019). Advances in understanding DNA processing and protection at stalled replication forks. JOURNAL OF CELL BIOLOGY. 218 (4): 1096-1107

Kottemann, Molly C.; Smogorzewska, Agata. (2013). Fanconi anaemia and the repair of Watson and Crick DNA crosslinks. NATURE. 493 (7432): 356-363

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About the Author:

Ilaria Ceglia, Ph.D., Science Informationist - Ilaria joined the Markus Library Team in 2017. As science liaison between the Rockefeller scientific community and the library, Ilaria assists Rockefeller scientists find, and effectively use, the scholarly communication tools available at the library, provides customized literature searching, delivers research information reports and publications metric analysis to enhance collaborations between Rockefeller and leading scientific institutions, provides access to digital content to manage large data freely accessible. Ilaria manages a drug development database to perform clinical literature searches and drugs pipeline reports for Rockefeller research faculty, scientists and clinicians. As the NIH compliance monitor for the Rockefeller University, Ilaria helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to complement other resource center services, organize tutorial training sessions in areas of life sciences and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and PubMed literature searching, managing recommendation readings library blog for lectures and special seminars. Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New York, where she taught Cell Biology and Biochemistry. As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends and colleagues.