Recommended Readings: Brenda Schulman, Ph.D. Friday November 15, 2019

Recommended Readings: Brenda Schulman, Ph.D. Friday November 15, 2019

                                                                        Friday Lectures  

Brenda Shulman, PhD

Friday, November 15, 2019  3:45 p.m

Caspary Auditorium

Brenda Schulman, Ph.D.

Director and Scientific Member

Department of Molecular Machines and Signaling

Max Planck Institute of Biochemistry

How a Ubiquitin-like Protein Brings Ubiquitylation to Life


Recommended Readings:

Empirical Articles

Huttenhain, Ruth; Xu, Jiewei; Burton, Lily A.; et al. (2019). ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. CELL HOST & MICROBE. 26 (1): 86- 99.e7

Scott, Daniel C.; Rhee, David Y.; Duda, David M.; et al. (2016). Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation. CELL. 166 (5): 1198-1214

Duda, David M.; Scott, Daniel C.; Calabrese, Matthew F.; et al. (2011). Structural regulation of cullin-RING ubiquitin ligase complexes. CURRENT OPINION IN STRUCTURAL BIOLOGY. 21 (2): 257-264

Zimmerman, Erik S.; Schulman, Brenda A.; Zheng, Ning. (2010). Structural assembly of cullin-RING ubiquitin ligase complexes. CURRENT OPINION IN STRUCTURAL BIOLOGY. 20 (6): 714-721

Huang, Danny T.; Ayrault, Olivier; Hunt, Harold W.; et al. (2009). E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification. MOLECULAR CELL. 33 (4): 483-495

Duda, David M.; Borg, Laura A.; Scott, Daniel C.; et al. (2008). Structural insights into NEDD8 activation of Cullin-RING ligases: Conformational control of conjugation. CELL. 134 (6): 995-1006

Review Papers

Enchev, Radoslav I.; Schulman, Brenda A.; Peter, Matthias. (2015). Protein neddylation: beyond cullin-RING ligases. NATURE REVIEWS MOLECULAR CELL BIOLOGY. 16 (1): 30-44

Lydeard, John R.; Schulman, Brenda A.; Harper, J. Wade. (2003). Building and remodelling Cullin-RING E3 ubiquitin ligases – ‘Ubiquitylation: mechanism and functions’ review series. EMBO REPORTS. 14 (12): 1050-1061

Book Chapters

Taherbhoy, Asad M.; Schulman, Brenda A.; Kaiser, Stephen E. (2012). Ubiquitin-like modifiers. LYSINE-BASED POST-TRANSLATIONAL MODIFICATION OF PROTEINS. 52: 51-63

Dye, Billy T.; Schulman, Brenda A. (2007). Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins. ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE. 36: 131-150

By |2019-11-05T20:10:32+00:00November 5th, 2019|Categories: Biochemistry, Drug Discovery, Friday Lectures, Recommended Readings, Structural Biology|Tags: , , , , , |Comments Off on Recommended Readings: Brenda Schulman, Ph.D. Friday November 15, 2019

About the Author:

Ilaria Ceglia, Ph.D., Science Informationist - Ilaria joined the Markus Library Team in 2017. As science liaison between the Rockefeller scientific community and the library, Ilaria assists Rockefeller scientists find, and effectively use, the scholarly communication tools available at the library, provides customized literature searching, delivers research information reports and publications metric analysis to enhance collaborations between Rockefeller and leading scientific institutions, provides access to digital content to manage large data freely accessible. Ilaria manages a drug development database to perform clinical literature searches and drugs pipeline reports for Rockefeller research faculty, scientists and clinicians. As the NIH compliance monitor for the Rockefeller University, Ilaria helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to complement other resource center services, organize tutorial training sessions in areas of life sciences and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and PubMed literature searching, managing recommendation readings library blog for lectures and special seminars. Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New York, where she taught Cell Biology and Biochemistry. As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends and colleagues.