Special Seminar Series
Wednesday, March 6, 2019 4:00 p.m.
Carson Family Auditorium
Christopher Chang, Ph.D.
Chair Professor
Department of Chemistry and Molecular and Cell Biology
University of California, Berkeley
Deciphering Transition Metal Signaling with Activity-Based Sensing
Recommended Readings:
Empirical Articles
Su TA, Shihadih DS, Cao W, Detomasi TC, Heffern MC, Jia S, Stahl A, Chang CJ. (2018). A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 140 (42): 13764–13774
Xiao, T.; Ackerman, C. M.; Carroll, E. C.; Jia, S.; et al. (2018). Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system. NATURE CHEMICAL BIOLOGY. 14: 655-663
Smith, P. T.; Benke, B. P.; Cao, Z.; Kim, et al. (2018). Iron Porphyrins Embedded into a Supramolecular Porous Organic Cage for Electrochemical CO2 Reduction in Water. ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 57: 9684-9688
Aron, Allegra T.; Loehr, Morten O.; Bogena, Jana; et al. (2016). An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 138 (43): 14338-14346
Dodani, Sheel C.; Firl, Alana; Chan, Jefferson; et al. (2014). Copper is an endogenous modulator of neural circuit spontaneous activity. PNAS. 11 (46): 16280-16285
Dodani, Sheel C.; Domaille, Dylan W.; Nam, Christine I.; et al. (2011). Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy. PNAS. 108 (15): 5980-5985
Review Papers
Chang CJ. (2017). Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness? ACCOUNTS OF CHEMICAL RESEARCH. 50 (3): 535-538
Ackerman, Cheri M.; Lee, Sumin; Chang, Christopher J. (2017). Analytical Methods for Imaging Metals in Biology: From Transition Metal Metabolism to Transition Metal Signaling. ANALYTICAL CHEMISTRY. 89 (1): 22-41
Cotruvo, Joseph A., Jr.; Aron, Allegra T.; Ramos-Torres, Karla M. et al. (2015). Synthetic fluorescent probes for studying copper in biological systems. CHEMICAL SOCIETY REVIEWS. 44 (13): 4400-4414