Friday Lecture Series
(open to the Rockefeller community)
Friday, February 11, 2022
Enrique M. De La Cruz, Ph.D.
Professor and Chair
Department of Molecular Biophysics and Biochemistry
Head of Branford College
Yale University
How Cells use Chemistry and Physics to Break and Remodel the Bones that Power their Movement
Recommended Readings:
Empirical Articles
Bibeau, J. P., Gray, S., & De La Cruz, E. M. (2021). Clusters of a Few Bound Cofilins Sever Actin Filaments. Journal of molecular biology, 433(7), 166833.
Hocky, G. M., Sindelar, C. V., Cao, W., Voth, G. A., & De La Cruz, E. M. (2021). Structural basis of fast- and slow-severing actin-cofilactin boundaries. The Journal of biological chemistry, 296, 100337.
Pandit, N. G., Cao, W., Bibeau, J., Johnson-Chavarria, E. M., Taylor, E. W., Pollard, T. D., & De La Cruz, E. M. (2020). Force and phosphate release from Arp2/3 complex promote dissociation of actin filament branches. Proceedings of the National Academy of Sciences of the United States of America, 117(24), 13519–13528.
Jermyn, A. S., Cao, W., Elam, W. A., De La Cruz, E. M., & Lin, M. M. (2020). Directional allosteric regulation of protein filament length. Physical review. E, 101(3-1), 032409.
Huehn, A. R., Bibeau, J. P., Schramm, A. C., Cao, W., De La Cruz, E. M., & Sindelar, C. V. (2020). Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments. Proceedings of the National Academy of Sciences of the United States of America, 117(3), 1478–1484.
Review Articles
De La Cruz, E. M., & Gardel, M. L. (2015). Actin Mechanics and Fragmentation. The Journal of biological chemistry, 290(28), 17137–17144.
