Hybrid Friday Lecture Series
(open to the Rockefeller and Tri-Institutional communities)
Friday, February 2, 2024
Donita Brady, Ph.D.
Harrison McCrea Dickson, M.D. and Clifford C. Baker, M.D. Presidential Professor and Assistant Dean for Inclusion, Diversity, and Equity in Research Training, department of cancer biology, University of Pennsylvania Perelman School of Medicine; Associate Investigator, Abramson Family Cancer Research Institute; Full Member, Abramson Cancer Center Tumor Biology Program
Copper-Dependent Nutrient Signaling and Metabolism Vulnerabilities in Cancer
Recommended Readings:
Chang, Christopher J., and Donita C. Brady. “Capturing copper to inhibit inflammation.” Nature Chemical Biology 19.8 (2023): 937-939.
Ge, Eva J., et al. “Connecting copper and cancer: from transition metal signalling to metalloplasia.” Nature Reviews Cancer 22.2 (2022): 102-113.
Cobine, Paul A., and Donita C. Brady. “Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death.” Molecular Cell 82.10 (2022): 1786-1787.
Tsvetkov, Peter, et al. “Copper induces cell death by targeting lipoylated TCA cycle proteins.” Science 375.6586 (2022): 1254-1261.
Tsang, Tiffany, Caroline I. Davis, and Donita C. Brady. “Copper biology.” Current Biology 31.9 (2021): R421-R427.