Webinar Friday Lecture Series
(open to the Rockefeller community)
Friday, February 4, 2022
Gabriel D. Victora, Ph.D.
Laurie and Peter Grauer Assistant Professor
Head of the Laboratory of Lymphocyte Dynamics
The Rockefeller University
Clonal and Cellular Dynamics of the Antibody Response
Recommended Readings:
Empirical Articles
Mesin, L., Bilate, A. M., Schiepers, A., Shalek, A. K., Rudensky, A. Y., & Victora, G. D. (2021). Expression of Foxp3 by T follicular helper cells in end-stage germinal centers. Science, 373(6552), eabe5146.
Pae, J., Ersching, J., Castro, T., Schips, M., Mesin, L., Allon, S. J., Ordovas-Montanes, J., Mlynarczyk, C., Melnick, A., Efeyan, A., Shalek, A. K., Meyer-Hermann, M., & Victora, G. D. (2021). Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. The Journal of experimental medicine, 218(4), e20201699.
Mesin, L., Schiepers, A., Ersching, J., Barbulescu, A., Cavazzoni, C. B., Angelini, A., Okada, T., Kurosaki, T., & Victora, G. D. (2020). Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting. Cell, 180(1), 92–106.e11.
Jacobsen, J. T., Mesin, L., Markoulaki, S., Schiepers, A., Cavazzoni, C. B., Bousbaine, D., Jaenisch, R., & Victora, G. D. (2018). One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation. The Journal of experimental medicine, 215(10), 2686–2695.
Ersching, J., Efeyan, A., Mesin, L., Jacobsen, J. T., Pasqual, G., Grabiner, B. C., Dominguez-Sola, D., Sabatini, D. M., & Victora, G. D. (2017). Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase. Immunity, 46(6), 1045–1058.e6.
Review Articles
Pae, J., Jacobsen, J. T., & Victora, G. D. (2021). Imaging the different timescales of germinal center selection. Immunological reviews, 10.1111/imr.13039.