Webinar Monday Lecture Series
(open to the Rockefeller community)
Monday, March 8, 2021
Luciano Marraffini, Ph.D.
Professor and Head
Laboratory of Bacteriology
The Rockefeller University
CRISPR-Cas13 Immunity: Sacrificing the Host for the Population
Recommended Readings:
Empirical Articles
Meeske, Alexander J.; Jia, Ning; Cassel, Alice K.; et al. (2020). A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity. SCIENCE. 369 (6499): 54-59
Meeske, Alexander J.; Nakandakari-Higa, Sandra; Marraffini, Luciano A. (2019). Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage. NATURE. 570 (7760): 241-245
Meeske, Alexander J.; Marraffini, Luciano A. (2018). RNA Guide Complementarity Prevents Self-Targeting in Type VI CRISPR Systems. MOLECULAR CELL. 71 (5): 791-801
Marraffini, Luciano A. (2015). CRISPR-Cas immunity in prokaryotes. NATURE. 526 (7571): 55-61
Cong, Le; Ran, F. Ann; Cox, David; et al. (2013). Multiplex Genome Engineering Using CRISPR/Cas Systems. SCIENCE. 339 (6121): 819-823
Review Papers
Varble, Andrew; Marraffini, Luciano A. (2019). Three New Cs for CRISPR: Collateral, Communicate, Cooperate. TRENDS IN GENETICS. 35 (6): 446-456
Marraffini, Luciano A. (2015). CRISPR-Cas immunity in prokaryotes. NATURE. 526: 7571
Barrangou, Rodolphe; Marraffini, Luciano A. (2014). CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity. MOLECULAR CELL. 54 (2): 234-244
Book Chapters
Nussenzweig, Philip M.; Marraffini, Luciano A. (2020). Molecular Mechanisms of CRISPR-Cas Immunity in Bacteria. ANNUAL REVIEW OF GENETICS. 54: 93-120
Jiang, Wenyan; Marraffini, Luciano A. (2015). CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems. ANNUAL REVIEW OF MICROBIOLOGY. 69: 209-228