Webinar Friday Lecture Series
(open to the Tri-I community)
Friday, January 15, 2021
Wade Harper, Ph.D.
Bert and Natalie Vallee Professor of Molecular Pathology and Chair
Department of Cell Biology
Harvard Medical School
Understanding Selective Organelle Remodeling by Autophagy
Recommended Readings:
Empirical Articles
Ordureau, Alban; Paulo, Joao A.; Zhang, Jiuchun; et al. (2020). Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling. MOLECULAR CELL. 77 (5): 1124-1142
McKenna, Michael J.; Sim, Sue Im; Ordureau, Alban; et al. (2020). The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. Science. 369 (6511): 1583-+
An, Heeseon; Ordureau, Alban; Koerner, Maria; et al. (2020). Systematic quantitative analysis of ribosome inventory during nutrient stress. NATURE. 583 (7815): 303-309
Ordureau, Alban; Paulo, Joao A.; Zhang, Wei; et al. (2018). Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. MOLECULAR CELL. 70 (2): 211-
Ordureau, Alban; Heo, Jin-Mi; Duda, David M.; et al. (2015). Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. PNAS. 112 (21): 6637-6642
Ordureau, Alban; Sarraf, Shireen A.; Duda, David M.; et al. (2014). Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis. MOLECULAR CELL. 56 (3): 360-375
Sarraf, Shireen A.; Raman, Malavika; Guarani-Pereira, Virginia; et al. (2013). Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. NATURE. 496 (7445): 372-376
Review Papers
An, Heeseon; Harper, J. Wade. (2020). Ribosome Abundance Control Via the Ubiquitin-Proteasome System and Autophagy. JOURNAL OF MOLECULAR BIOLOGY. 432 (1)
Harper, J. Wade; Ordureau, Alban; Heo, Jin-Mi. (2018). Building and decoding ubiquitin chains for mitophagy. NATURE REVIEWS MOLECULAR CELL BIOLOGY. 19 (2): 93-108
Galluzzi, Lorenzo; Baehrecke, Eric H.; Ballabio, Andrea; et al. (2017). Molecular definitions of autophagy and related processes. EMBO JOURNAL. 36 (13): 1811-1836
Klionsky, Daniel J.; Abdelmohsen, Kotb; Abe, Akihisa; et al. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). AUTOPHAGY. 12 (1): 1-222