Friday Lectures
Friday, February 28, 2020 3:45 p.m.
Caspary Auditorium
Luciano Marraffini, Ph.D.
Professor and Head
Laboratory of Bacteriology
The Rockefeller University
CRISPR-Cas10: When DNA Cleavage Just Isn’t Enough
Recommended Readings:
Empirical Articles
Wang, Ling; Mo, Charlie Y.; Wasserman, Michael R.; et al. (2019). Dynamics of Cas10 Govern Discrimination between Self and Non-self in Type III CRISPR-Cas Immunity. MOLECULAR CELL Volume. 73 (2): 278-+
Rostol, Jakob T.; Marraffini, Luciano A. (2019). Non-specific degradation of transcripts promotes plasmid clearance during type III-A CRISPR-Cas immunity. NATURE MICROBIOLOGY. 4 (4): 656-662
Samai, Poulami; Pyenson, Nora; Jiang, Wenyan; et al. (2015). Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity. CELL. 161 (5): 1164-1174
Marraffini, Luciano A. (2015). CRISPR-Cas immunity in prokaryotes. NATURE. 526 (7571): 55-61
Cong, Le; Ran, F. Ann; Cox, David; et al. (2013). Multiplex Genome Engineering Using CRISPR/Cas Systems. SCIENCE. 339 (6121): 819-823
Review Papers
Varble, Andrew; Marraffini, Luciano A. (2019). Three New Cs for CRISPR: Collateral, Communicate, Cooperate. TRENDS IN GENETICS. 35 (6): 446-456
Pyenson, Nora C.; Marraffini, Luciano A. (2017). Type III CRISPR-Cas systems: when DNA cleavage just isn’t enough. CURRENT OPINION IN MICROBIOLOGY. 37: 150-154
Marraffini, Luciano A. (2015). CRISPR-Cas immunity in prokaryotes. NATURE. 526: 7571
Barrangou, Rodolphe; Marraffini, Luciano A. (2014). CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity. MOLECULAR CELL. 54 (2): 234-244
Book Chapter
Jiang, Wenyan; Marraffini, Luciano A. (2015). CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems. ANNUAL REVIEW OF MICROBIOLOGY. 69: 209-228