Friday Lectures
Friday, September 27, 2019 3:45 p.m
Caspary Auditorium
Charles L. Sawyers M.D.
Marie-Josée and Henry Kravis Chair
Department of Human Oncology and Pathogenesis
Memorial Sloan Kettering Cancer Center
Lineage Plasticity in Prostate Cancer
Recommended Readings:
Science News
Matthew Tontonoz. Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype. June 26, 2019. On Cancer
Empirical Articles
Adams, Elizabeth J.; Karthaus, Wouter R.; Hoover, Elizabeth; et al. (2019). FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes. NATURE. 571 (7765): 408-412
Mu, Ping; Zhang, Zeda; Benelli, Matteo; et al. (2017). SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer. SCIENCE. 355 (6320): 84-88
Bose, Rohit; Karthaus, Wouter R.; Armenia, Joshua; et al. (2017). ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis. NATURE. 546 (7660): 671-675
Gao, Dong; Vela, Ian; Sboner, Andrea; et al. (2014). Organoid Cultures Derived from Patients with Advanced Prostate Cancer. CELL. 159 (1): 176-187
Review Paper
Watson, Philip A.; Arora, Vivek K.; Sawyers, Charles L. (2015). Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer. NATURE REVIEWS CANCER. 15 (12): 701-711
Book Chapter
Watson, Philip A.; Sawyers, Charles L. (2009). Molecular Biology of Novel Targets Identified Through Study of Castration-Recurrent Prostate Cancer. ANDROGEN ACTION IN PROSTATE CANCER. 743-754
Ilaria Ceglia, Ph.D., Science Informationist -
Ilaria joined the Markus Library Team in 2017. As science liaison
between the Rockefeller scientific community and the library, Ilaria
assists Rockefeller scientists find, and effectively use, the scholarly
communication tools available at the library, provides customized
literature searching, delivers research information reports and
publications metric analysis to enhance collaborations between
Rockefeller and leading scientific institutions, provides access to digital
content to manage large data freely accessible. Ilaria manages a drug
development database to perform clinical literature searches and drugs
pipeline reports for Rockefeller research faculty, scientists and clinicians.
As the NIH compliance monitor for the Rockefeller University, Ilaria
helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains
compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to
complement other resource center services, organize tutorial training sessions in areas of life sciences
and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and
PubMed literature searching, managing recommendation readings library blog for lectures and special
seminars.
Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul
Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at
Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New
York, where she taught Cell Biology and Biochemistry.
As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends
and colleagues.