Friday, October 27, 2017 3:45 p.m.
Caspary Auditorium
Sean F. Brady, Ph.D.
Evnin Associate Professor and Head
Laboratory of Genetically Encoded Small Molecules
The Rockefeller University
Watch your step, there is new chemistry everywhere
Recommended Readings:
Cohen LJ, Han S, Huang YH, Brady SF. (2017). Identification of the Colicin V Bacteriocin Gene Cluster by Functional Screening of a Human Microbiome Metagenomic Library. ACS Infect Dis. In Press doi: 10.1021/acsinfecdis.7b00081
Fierer, Noah (2017). Embracing the unknown: disentangling the complexities of the soil microbiome. NATURE REVIEWS MICROBIOLOGY. 15 (10): 579-590
Chu, John; Vila-Farres, Xavier; Inoyama, Daigo; et al. (2016). Discovery of MRSA active antibiotics using primary sequence from the human microbiome. NATURE CHEMICAL BIOLOGY. 12 (12): 1004-+
O’Brien, Sarah L.; Gibbons, Sean M.; Owens, Sarah M.; et al. (2016). Spatial scale drives patterns in soil bacterial diversity. ENVIRONMENTAL MICROBIOLOGY. 18 (6): 2039-2051
Medema, Marnix H.; Kottmann, Renzo; Yilmaz, Pelin; et al. (2015). Minimum Information about a Biosynthetic Gene cluster. NATURE CHEMICAL BIOLOGY. (11) 9: 625-631
Owen, Jeremy G.; Reddy, Boojala Vijay B.; Ternei, Melinda A.; et al. (2013). Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products. PNAS. 110 (29): 11797-11802