Friday Lecture Series
Friday, February 5, 2016
3:45 p.m., Carson Family Caspary Auditorium
James M. Wells, Ph.D.
Professor of Pediatrics,
Perinatal Institute Endowed Professor,
Division of Development Biology,
Director for Basic Research,
Division of Endocrinology,
Cincinnati Children’s Hospital Medical Center
Pluripotent Stem Cell-based Models of Human Gastrointestinal Development and Disease
Recommended Reading
Empirical Articles
McCracken, K. W., Catá, E. M., Crawford, C. M., Sinagoga, K. L., Schumacher, M., Rockich, B. E., … & Wells, J. M. (2014). Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature. 516(7531):400-404. doi: 10.1038/nature13863.
Spence, J. R., Mayhew, C. N., Rankin, S. A., Kuhar, M. F., Vallance, J. E., Tolle, K., … & Shroyer, N. F. (2011). Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature, 470(7332), 105-109. doi: 10.1038/nature09691
Watson, C. L., Mahe, M. M., Múnera, J., Howell, J. C., Sundaram, N., Poling, H. M., … & Grabowski, G. (2014). An in vivo model of human small intestine using pluripotent stem cells. Nature Medicine, 20(11), 1310-1314. doi: 10.1038/nm.3737
Review Papers
Sinagoga, K. L., & Wells, J. M. (2015). Generating human intestinal tissues from pluripotent stem cells to study development and disease. The EMBO Journal, 34(9):1149-63. doi: 10.15252/embj.201490686
Wells, J. M., & Spence, J. R. (2014). How to make an intestine. Development, 141(4), 752-760. doi: 10.1242/dev.097386.
