Friday Lecture Series
Friday, March 13, 2015
3:45 p.m., Caspary Auditorium
Jef Boeke, Ph.D.
Professor,
Department of Biochemistry and Molecular Pharmacology,
Director, Institute for systems genetics,
New York University
Synthesis of Designer Chromosomes from Scratch
Recommended Readings
Empirical Articles
Annaluru, N., Muller, H., Mitchell, L. a, Ramalingam, S., Stracquadanio, G., Richardson, S. M., … Chandrasegaran, S. (2014). Total synthesis of a functional designer eukaryotic chromosome. Science, 344(6179), 55–58. doi:10.1126/science.1249252
Dymond, J. S., Richardson, S. M., Coombes, C. E., Babatz, T., Muller, H., Annaluru, N., … Boeke, J. D. (2011). Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature, 477(7365), 471–476. doi:10.1038/nature10403
Mitchell, L. a., & Boeke, J. D. (2014). Circular permutation of a synthetic eukaryotic chromosome with the telomerator. Proceedings of the National Academy of Sciences, 111(48), 17003–17010. doi:10.1073/pnas.1414399111
Reviews and Protocols
Cooper, E. M., Müller, H., Chandrasegaran, S., Bader, J. S., & Boeke, J. D. (2012). The build-a-genome course. Methods in Molecular Biology, 852, 273–283. doi:10.1007/978-1-61779-564-0_20
