Friday Lecture Series
(open to the Rockefeller community)
Friday, December 10, 2021
Kivanç Birsoy, Ph.D.
Chapman Perelman Assistant Professor
Head of the Laboratory of Metabolic Regulation And Genetics
The Rockefeller University
Deciphering the Role of Oxidative Metabolism in Cancer
Recommended Readings:
Empirical Articles
Wang, Y., Yen, F. S., Zhu, X. G., Timson, R. C., Weber, R., Xing, C., Liu, Y., Allwein, B., Luo, H., Yeh, H. W., Heissel, S., Unlu, G., Gamazon, E. R., Kharas, M. G., Hite, R., & Birsoy, K. (2021). SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells. Nature, 599(7883), 136–140.
Rex, M. R., Williams, R., Birsoy, K., Ta Llman, M. S., & Stahl, M. (2021). Targeting mitochondrial metabolism in acute myeloid leukemia. Leukemia & lymphoma, 1–8.
Zhu, X. G., Chudnovskiy, A., Baudrier, L., Prizer, B., Liu, Y., Ostendorf, B. N., Yamaguchi, N., Arab, A., Tavora, B., Timson, R., Heissel, S., de Stanchina, E., Molina, H., Victora, G. D., Goodarzi, H., & Birsoy, K. (2021). Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. Cell metabolism, 33(1), 211–221.e6.
Soula, M., Weber, R. A., Zilka, O., Alwaseem, H., La, K., Yen, F., Molina, H., Garcia-Bermudez, J., Pratt, D. A., & Birsoy, K. (2020). Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers. Nature chemical biology, 16(12), 1351–1360.
Guarecuco, R., Williams, R. T., Baudrier, L., La, K., Passarelli, M. C., Ekizoglu, N., Mestanoglu, M., Alwaseem, H., Rostandy, B., Fidelin, J., Garcia-Bermudez, J., Molina, H., & Birsoy, K. (2020). Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells. Science advances, 6(41), eabc7120.
Review Articles
Soula, M., & Birsoy, K. (2021). STACKing the odds for discoveries. Nature chemical biology, 17(6), 627–628.
