Friday Lectures
Friday, May 31, 2019 3:45 p.m
Caspary Auditorium
Wolfgang Baumeister Ph.D.
Director
Department of Molecular Structural Biology
Max Planck Institute of Biochemistry
Structural Biology in situ: The Promise and Challenges of Cryo-Electron Tomography
Recommended Readings:
Science News
Structural biology: The Max Planck Institute of Biochemistry. March 11, 2019. SciTech Europa
Empirical Articles
Majumder, Parijat; Rudack, Till; Beck, Florian; et al. (2019). Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. PNAS. 116 (2): 534-539
Liang, Yi-Lynn; Khoshouei, Maryam; Deganutti, Giuseppe; et al. (2018). Cryo-EM structure of the active, G(s)- protein complexed, human CGRP receptor. NATURE. 561 (7724): 492-+
Mahamid, Julia; Pfeffer, Stefan; Schaffer, Miroslava; et al. (2016). Visualizing the molecular sociology at the HeLa cell nuclear periphery. SCIENCE. 351 (6276): 969-972
Liang, Yi-Lynn; Khoshouei, Maryam; Radjainia, Mazdak; et al. (2017). Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. NATURE. 546 (7656): 118-+
Beck, Florian; Unverdorben, Pia; Bohn, Stefan; et al. (2012). Near-atomic resolution structural model of the yeast 26S proteasome. PNAS. 109 (37): 14870-14875
Review Papers
Erdmann, Philipp S.; Plitzko, Juergen M.; Baumeister, Wolfgang. (2018). Addressing cellular compartmentalization by in situ cryo-electron tomography. CURRENT OPINION IN COLLOID & INTERFACE SCIENCE. 34: 89-99. PLEASE REQUEST FROM MARKUS LIBRARY.
Beck, Martin; Baumeister, Wolfgang. (2016). Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail? TRENDS IN CELL BIOLOGY. 26 (11): 825-837
Lucic, Vladan; Rigort, Alexander; Baumeister, Wolfgang. (2013). Cryo-electron tomography: The challenge of doing structural biology in situ. JOURNAL OF CELL BIOLOGY. 202 (3): 407-419
Book Chapter
Kourkoutis, Lena Fitting; Plitzko, Juergen M.; Baumeister, Wolfgang. (2012). Electron Microscopy of Biological Materials at the Nanometer Scale. ANNUAL REVIEW OF MATERIALS RESEARCH. 42: 33-58