Friday Lecture Series
(open to the Rockefeller and Tri-Institutional communities)
Friday, November 7, 2025
Itai Yanai, Ph.D.
Professor, Department of Biochemistry and Molecular Pharmacology, Institute for Systems Genetics, New York University Grossman School of Medicine
Mechanisms of Cellular Plasticity and Adaptive Gene Regulation
Recommended Readings:
Hunter, Miranda V., et al. “Mechanical confinement governs phenotypic plasticity in melanoma.” Nature (2025): 1-11.
Frank, Steven A., and Itai Yanai. “The origin of novel traits in cancer.” Trends in Cancer (2024).
França, Gustavo S., et al. “Cellular adaptation to cancer therapy along a resistance continuum.” Nature 631.8022 (2024): 876-883.
Patel, Ayushi S., and Itai Yanai. “A developmental constraint model of cancer cell states and tumor heterogeneity.” Cell 187.12 (2024): 2907-2918.
Barkley, Dalia, et al. “Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment.” Nature genetics 54.8 (2022): 1192-1201.
