Friday Lecture Series
(open to the Rockefeller and Tri-I community)
Friday, March 03, 2023
Jeffrey Gordon, M.D.
Dr. Robert J. Glaser Distinguished University Professor,
Director, The Edison Family Center for Genome Sciences and Systems Biology,
Washington University School of Medicine,
St. Louis, MO
Developing Microbiome-directed Therapeutics for Treating Childhood Undernutrition
Recommended Readings:
Empirical Articles
Mostafa, I., Fahim, S. M., Das, S., Gazi, M. A., Hasan, M. M., Saqeeb, K. N., Mahfuz, M., Lynn, H. B., Barratt, M. J., Gordon, J. I., & Ahmed, T. (2022). Developing shelf-stable Microbiota Directed Complementary Food (MDCF) prototypes for malnourished children: study protocol for a randomized, single-blinded, clinical study. BMC pediatrics, 22(1), 385.
Han, N. D., Cheng, J., Delannoy-Bruno, O., Webber, D., Terrapon, N., Henrissat, B., Rodionov, D. A., Arzamasov, A. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S., Desai, C., Marion, S., Barratt, M. J., Heath, A. C., & Gordon, J. I. (2022). Microbial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans. Cell, 185(14), 2495–2509.e11.
Barratt, M. J., Ahmed, T., & Gordon, J. I. (2022). Gut microbiome development and childhood undernutrition. Cell host & microbe, 30(5), 617–626.
Weagley, J. S., Zaydman, M., Venkatesh, S., Sasaki, Y., Damaraju, N., Yenkin, A., Buchser, W., Rodionov, D. A., Osterman, A., Ahmed, T., Barratt, M. J., DiAntonio, A., Milbrandt, J., & Gordon, J. I. (2022). Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition. Cell reports, 39(4), 110738.
Barratt, M. J., Nuzhat, S., Ahsan, K., Frese, S. A., Arzamasov, A. A., Sarker, S. A., Islam, M. M., Palit, P., Islam, M. R., Hibberd, M. C., Nakshatri, S., Cowardin, C. A., Guruge, J. L., Byrne, A. E., Venkatesh, S., Sundaresan, V., Henrick, B., Duar, R. M., Mitchell, R. D., Casaburi, G., … Gordon, J. I. (2022). Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition. Science translational medicine, 14(640), eabk1107
