Monday Lecture Series
(open to the Rockefeller community)
Monday, October 31, 2022
Mary Elizabeth Hatten, Ph.D.
Frederick P. Rose Professor,
Head of the Laboratory of Developmental Neurobiology,
The Rockefeller University
New Insights into the Formation and Function of the Cerebellum
Recommended Readings:
Empirical Articles
Behesti, H., Kocabas, A., Buchholz, D. E., Carroll, T. S., & Hatten, M. E. (2021). Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells. eLife, 10, e67074.
Buchholz, D. E., Carroll, T. S., Kocabas, A., Zhu, X., Behesti, H., Faust, P. L., Stalbow, L., Fang, Y., & Hatten, M. E. (2020). Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics. Proceedings of the National Academy of Sciences of the United States of America, 117(26), 15085–15095.
Minis, A., Rodriguez, J. A., Levin, A., Liu, K., Govek, E. E., Hatten, M. E., & Steller, H. (2019). The proteasome regulator PI31 is required for protein homeostasis, synapse maintenance, and neuronal survival in mice. Proceedings of the National Academy of Sciences of the United States of America, 116(49), 24639–24650.
Penas, C., Maloof, M. E., Stathias, V., Long, J., Tan, S. K., Mier, J., Fang, Y., Valdes, C., Rodriguez-Blanco, J., Chiang, C. M., Robbins, D. J., Liebl, D. J., Lee, J. K., Hatten, M. E., Clarke, J., & Ayad, N. G. (2019). Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis. Nature communications, 10(1), 3028.
Lara, P., Tellgren-Roth, Å., Behesti, H., Horn, Z., Schiller, N., Enquist, K., Cammenberg, M., Liljenström, A., Hatten, M. E., von Heijne, G., & Nilsson, I. (2019). Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase. The Journal of biological chemistry, 294(12), 4538–4545.
