Recommended Readings: Nevan Krogan, Ph.D., September 30th, 2022

Recommended Readings: Nevan Krogan, Ph.D., September 30th, 2022

Friday Lecture Series

(open to the Rockefeller community)

Friday, September 30, 2022

Nevan Krogan, Ph.D.

Director of the HARC Center,
Co-Director of the Cancer Cell Mapping Initiative (CCMI), the Host Pathogen Map Initiative (HPMI) and the Psychiatric Cell Map Initiative (PCMI),
Director of the California Institute for Quantitative Biosciences,
Director of the Quantitative Biosciences Institute,
Senior Investigator of the J. David Gladstone Institutes,
Professor, Cellular Molecular Pharmacology,
University of California, San Francisco

 

Using Systems Approaches to Understand Mechanisms in Disease

Recommended Readings:

Empirical Articles

Chen, H., Diolaiti, M. E., O’Leary, P. C., Rojc, A., Krogan, N. J., Kim, M., & Ashworth, A. (2022). A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor. Molecular cancer therapeutics, 21(7), 1076–1089.

Johnson, J. R., Crosby, D. C., Hultquist, J. F., Kurland, A. P., Adhikary, P., Li, D., Marlett, J., Swann, J., Hüttenhain, R., Verschueren, E., Johnson, T. L., Newton, B. W., Shales, M., Simon, V. A., Beltrao, P., Frankel, A. D., Marson, A., Cox, J. S., Fregoso, O. I., Young, J. A. T., & Krogan, N. J. (2022). Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling. Cell reports, 39(2), 110690.

Hiatt, J., Hultquist, J. F., McGregor, M. J., Bouhaddou, M., Leenay, R. T., Simons, L. M., Young, J. M., Haas, P., Roth, T. L., Tobin, V., Wojcechowskyj, J. A., Woo, J. M., Rathore, U., Cavero, D. A., Shifrut, E., Nguyen, T. T., Haas, K. M., Malik, H. S., Doudna, J. A., May, A. P., Marson, A., & Krogan, N. J. (2022). A functional map of HIV-host interactions in primary human T cells. Nature communications, 13(1), 1752.

Gordon, D. E., Hiatt, J., Bouhaddou, M., Rezelj, V. V., Ulferts, S., Braberg, H., Jureka, A. S., Obernier, K., Guo, J. Z., Batra, J., Kaake, R. M., Weckstein, A. R., Owens, T. W., Gupta, M., Pourmal, S., Titus, E. W., Cakir, M., Soucheray, M., McGregor, M., Cakir, Z., … Krogan, N. J. (2020). Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science, 370(6521), eabe9403.

By |2022-09-23T20:58:41+00:00September 23rd, 2022|Categories: Cellular and Molecular Pharmacology, Friday Lectures|Tags: , |Comments Off on Recommended Readings: Nevan Krogan, Ph.D., September 30th, 2022

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