Friday Lecture Series
(open to the Rockefeller community)
Friday, June 3, 2022
Magdalena Zernicka-Goetz, Ph.D., FMedSci
Bren Professor of Biology and Biological Engineering
California Institute of Technology, Pasadena, USA
Fellow of Sidney Sussex College
Professor of Mammalian Development and Stem Cell Biology,
Department of Physiology, Development and Neuroscience,
University of Cambridge, Cambridge, UK
Deconstructing and Reconstructing Embryos with Stem Cells – The Principles of Self-Organisation
Recommended Readings:
Empirical Articles
Shen, C., Lamba, A., Zhu, M., Zhang, R., Zernicka-Goetz, M., & Yang, C. (2022). Stain-free detection of embryo polarization using deep learning. Scientific reports, 12(1), 2404.
Duethorn, B., Groll, F., Rieger, B., Drexler, H., Brinkmann, H., Kremer, L., Stehling, M., Borowski, M. T., Mildner, K., Zeuschner, D., Zernicka-Goetz, M., Stemmler, M. P., Busch, K. B., Vaquerizas, J. M., & Bedzhov, I. (2022). Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism. Nature communications, 13(1), 610.
Sozen, B., Jorgensen, V., Weatherbee, B., Chen, S., Zhu, M., & Zernicka-Goetz, M. (2021). Reconstructing aspects of human embryogenesis with pluripotent stem cells. Nature communications, 12(1), 5550.
Zhu, M., Shahbazi, M., Martin, A., Zhang, C., Sozen, B., Borsos, M., Mandelbaum, R. S., Paulson, R. J., Mole, M. A., Esbert, M., Titus, S., Scott, R. T., Campbell, A., Fishel, S., Gradinaru, V., Zhao, H., Wu, K., Chen, Z. J., Seli, E., de Los Santos, M. J., & Zernicka Goetz, M. (2021). Human embryo polarization requires PLC signaling to mediate trophectoderm specification. eLife, 10, e65068.
Rawlings, T. M., Makwana, K., Taylor, D. M., Molè, M. A., Fishwick, K. J., Tryfonos, M., Odendaal, J., Hawkes, A., Zernicka-Goetz, M., Hartshorne, G. M., Brosens, J. J., & Lucas, E. S. (2021). Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. eLife, 10, e69603
