Webinar Friday Lecture Series
(open to the Tri-I community)
Friday, March 12, 2021
M. Celeste Simon, Ph.D.
Arthur H. Rubenstein, MBBCh Professor
Department of Cell and Developmental Biology
University of Pennsylvania
Stressful Microenvironments and Tumor Progression
Recommended Readings:
Empirical Articles
Li, Fuming; Huangyang, Peiwei; Burrows, Michelle; et al. (2020). FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome. NATURE CELL BIOLOGY. 22 (6): 728-739
Lee, Pearl; Malik, Dania; Perkons, Nicholas; et al. (2020). Targeting glutamine metabolism slows soft tissue sarcoma growth. NATURE COMMUNICATIONS. 11 (498)
Anderson, Nicole M.; Simon, M. Celeste. (2020). The tumor microenvironment. CURRENT BIOLOGY. 30 (16): R921-R925
Devalaraja, Samir; To, Tsun Ki Jerrick; Folkert, Ian W.; et al. (2020). Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression. CELL. 180 (6): 1098-1114
Bansal, Ankita; Sanchez, Danielle J.; Nimgaonkar, Vivek; et al. (2019). Gamma-Glutamyltransferase 1 Promotes Clear Cell Renal Cell Carcinoma Initiation and Progression. MOLECULAR CANCER RESEARCH. 17 (9): 1881-1892
Review Papers
Li, Fuming; Simon, M. Celeste. (2020). Cancer Cells Don’t Live Alone: Metabolic Communication within Tumor Microenvironments. DEVELOPMENTAL CELL. 54 (2): 183-195
Nakazawa, Michael S.; Keith, Brian; Simon, M. Celeste. (2016). Oxygen availability and metabolic adaptations. NATURE REVIEWS CANCER. 16 (10): 663-673
Majmundar, Amar J.; Wong, Waihay J.; Simon, M. Celeste. (2010). Hypoxia-Inducible Factors and the Response to Hypoxic Stress. MOLECULAR CELL. 40 (2): 294-309
Book Chapters
Li, Fuming; Lee, Kyoung Eun; Simon, M. Celeste. (2018). Detection of Hypoxia and HIF in Paraffin-Embedded Tumor Tissues. HYPOXIA: METHODS AND PROTOCOLS. 1742: 277-282
Imtiyaz, Hongxia Z.; Simon, M. Celeste. (2010). Hypoxia-Inducible Factors as Essential Regulators of Inflammation. DIVERSE EFFECTS OF HYPOXIA ON TUMOR PROGRESSION. 345: 105-120