Webinar Friday Lecture Series
(open to the Tri-I community)
Friday, September 25, 2020
Sean Morrison, Ph.D.
Director and Professor
Department of Pediatrics
University of Texas Southwestern
How the Niche Regulates Blood and Bone-Forming Stem Cells in the Marrow
Recommended Readings:
Empirical Articles
Comazzetto, Stefano; Murphy, Malea M.; Berto, Stefano; et al. (2019). Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor plus Niche Cells in the Bone Marrow. CELL STEM CELL. 24 (3): 477-+
Zhou, Bo O.; Yu, Hua; Yue, Rui; et al. (2017). Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF. NATURE CELL BIOLOGY. 19 (8): 891-+
Inra, Christopher N.; Zhou, Bo O.; Acar, Melih; et al. (2015). A perisinusoidal niche for extramedullary haematopoiesis in the spleen. NATURE. 527 (7579): 466-+
Acar, Melih; Kocherlakota, Kiranmai S.; Murphy, Malea M.; et al. (2015). Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. NATURE. 526 (7571): 126-+
Pitt, Lauren A.; Tikhonova, Anastasia N.; Hu, Hai; et al. (2015). CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance. CANCER CELL. 27 (6): 755-768
Zhou, Bo O.; Ding, Lei; Morrison, Sean J. (2015). Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1. ELIFE. 4
Burberry, Aaron; Zeng, Melody Y.; Ding, Lei; et al. (2014). Infection Mobilizes Hematopoietic Stem Cells through Cooperative NOD-like Receptor and Toll-like Receptor Signaling. CELL HOST & MICROBE. 15 (6): 779-791
Review Papers
Crane, Genevieve M.; Jeffery, Elise; Morrison, Sean J. (2017). Adult haematopoietic stem cell niches. NATURE REVIEWS IMMUNOLOGY. 17 (9): 573-590
Buszczak, Michael; Signer, Robert A. J.; Morrison, Sean J. (2014). Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis. CELL. 159(2): 242-251
Morrison, Sean J.; Scadden, David T. (2014). The bone marrow niche for haematopoietic stem cells. NATURE. 505 (7483): 327-334