Recommended Readings: Christopher D. Lima, Ph.D. Friday March 30th, 2018
Friday, March 30th, 2018 3:45 p.m.
Christopher D. Lima, Ph.D.
Structural Biology Program
Memorial Sloan Kettering Cancer Center
Targeting RNA for Degradation by the Eukaryotic RNA Exosome
Wasmuth, Elizabeth V.; Lima, Christopher D. (2017). The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome. NUCLEIC ACIDS RESEARCH. 45 (2): 846-860
Januszyk, Kurt; Lima, Christopher D. (2014). The eukaryotic RNA exosome. CURRENT OPINION IN STRUCTURAL BIOLOGY. 24: 132-140
Zinder, John C.; Wasmuth, Elizabeth V.; Lima, Christopher D. (2016). Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3. MOLECULAR CELL. 64 (4): 734-745
Wasmuth, Elizabeth V.; Januszyk, Kurt; Lima, Christopher D. (2014). Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. NATURE. 511 (7510): 435-+
Wasmuth, Elizabeth V.; Lima, Christopher D. (2012). Exo- and Endoribonucleolytic Activities of Yeast Cytoplasmic and Nuclear RNA Exosomes Are Dependent on the Noncatalytic Core and Central Channel. MOLECULAR CELL. 48 (1): 133-144
Liu, Quansheng; Greimann, Jaclyn C.; Lima, Christopher D. (2006). Reconstitution, activities, and structure of the eukaryotic RNA exosome. CELL. 127 (6): 1223-1237
Zinder, John C.; Lima, Christopher D. (2017). Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors. GENES & DEVELOPMENT. 31 (2): 88-100
Greimann, Jaclyn C.; Lima, Christopher D. (2008). RECONSTITUTION of RNA Exsomes From Human And Saccharomyces Cerevisiae: Clonning, Expression, Purification, And Activity Assays. METHODS IN ENZYMOLOGY. 448: 185-210
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Ilaria Ceglia, Ph.D., Science Informationist -
Ilaria joined the Markus Library Team in 2017. As science liaison
between the Rockefeller scientific community and the library, Ilaria
assists Rockefeller scientists find, and effectively use, the scholarly
communication tools available at the library, provides customized
literature searching, delivers research information reports and
publications metric analysis to enhance collaborations between
Rockefeller and leading scientific institutions, provides access to digital
content to manage large data freely accessible. Ilaria manages a drug
development database to perform clinical literature searches and drugs
pipeline reports for Rockefeller research faculty, scientists and clinicians.
As the NIH compliance monitor for the Rockefeller University, Ilaria
helps faculty to solve scientific submission requirements issues and ensures Rockefeller remains
compliant with NIH Public Access Policy. Her role also includes evaluate and select new databases to
complement other resource center services, organize tutorial training sessions in areas of life sciences
and on the use of reference management platforms F1000 Workspace, Scopus, Web of Science and
PubMed literature searching, managing recommendation readings library blog for lectures and special
Ilaria is a neuroscientist and a former Rockefeller postdoctoral and research associate of Dr. Paul
Greengard’s laboratory. She was a Research Assistant Professor at the Icahn School of Medicine at
Mount Sinai, New York and an Adjunct Assistant Professor at City College and Hunter College in New
York, where she taught Cell Biology and Biochemistry.
As an Italian expat living in New York, Ilaria is an enthusiastic proponent of Italian culture among friends