Friday Lectures
Friday, February 16th, 2018 3:45 p.m.
Caspary Auditorium
Gerald Crabtree, Ph.D.
David Korn Professor
Pathology and Developmental Biology
Stanford University
Chromatin regulation: Insights from new methods and the genomics of human disease
Recommended Readings:
Empirical Articles
Braun, Simon M. G.; Kirkland, Jacob G.; Chory, Emma J.; et al. (2017). Rapid and reversible epigenome editing by endogenous chromatin regulators. NATURE COMMUNICATIONS. 8
Stanton, Benjamin Z.; Hodges, Courtney; Calarco, Joseph P.; et al. (2017). Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin. NATURE GENETICS. 49 (2): 282-288
Kadoch, Cigall; Williams, Robert T.; Calarco, Joseph P.; et al. (2017). Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. NATURE GENETICS. 49 (2): 213-222
Miller, Erik L.; Hargreaves, Diana C.; Kadoch, Cigall; et al. (2017). TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. NATURE STRUCTURAL & MOLECULAR BIOLOGY. 24 (4): 344-+
Son, Esther Y.; Crabtree, Gerald R. (2014). The Role of BAF (mSWI/SNF) Complexes in Mammalian Neural Development. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS. 166 (3): 333-349
Hodges, Courtney; Crabtree, Gerald R. (2012). Dynamics of inherently bounded histone modification domains. PNAS. 109 (33): 13296-13301
Hathaway, Nathaniel A.; Bell, Oliver; Hodges, Courtney; et al. (2012). Dynamics and Memory of Heterochromatin in Living Cells. CELL. 149 (7): 1447-1460
Review Papers
Kadoch, Cigall; Crabtree, Gerald R. (2015). Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. SCIENCE ADVANCES. 1 (5)
Ho, Lena; Crabtree, Gerald R. (2010). Chromatin remodelling during development. NATURE. 463 (7280): 474-484
Book Chapter
Lessard, Julie A.; Crabtree, Gerald R. (2010). Chromatin Regulatory Mechanisms in Pluripotency. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. Book Series: Annual Review of Cell and Developmental Biology. 26: 503-532