Monday, October 23, 2017 3:45 p.m.
Carson Family Auditorium
Timothy Ryan, Ph.D.
Tri-Institutional Professor
Department of biochemistry
Weill Cornell Medical College
The Cost of Thinking: Metabolic Fitness at the Synapse Level
Recommended Readings:
Jaime de Juan Sanz (2017). The surprising metabolism of “exercising” neurons. Plos Blogs
http://news.cornell.edu/stories/2017/01/brain-cells-mobilize-sugar-response-increased-activity
Ashrafi, Ghazaleh; Ryan, Timothy A. (2017). Glucose metabolism in nerve terminals. CURRENT OPINION IN NEUROBIOLOGY. 45:156-161
Ashrafi, Ghazaleh; Wu, Zhuhao; Farrell, Ryan J.; et al. (2017). GLUT4 Mobilization Supports Energetic Demands of Active Synapses. NEURON. 93 (3): 606-+
Jang, SoRi; Nelson, Jessica C.; Bend, Eric G.; et al. (2016). Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function. NEURON. 90 (2): 278-291
Magistretti, Pierre J.; Allaman, Igor (2015). A Cellular Perspective on Brain Energy Metabolism and Functional Imaging. NEURON. 86 (4): 883-901
Rangaraju, Vidhya; Calloway, Nathaniel; Ryan, Timothy A.(2014). Activity-Driven Local ATP Synthesis Is Required for Synaptic Function. CELL. 156 (4): 825-835