Friday Lecture Series
(open to the Rockefeller community)
Friday, December 2, 2022
Gregory M. Alushin, Ph.D.
Assistant Professor,
Head of the Laboratory of Structural Biophysics and Mechanobiology
The Rockefeller University
Visualizing Cellular Force-sensing Through the Cytoskeleton
Recommended Readings:
Empirical Articles
Reynolds, M. J., Hachicho, C., Carl, A. G., Gong, R., & Alushin, G. M. (2022). Bending forces and nucleotide state jointly regulate F-actin structure. Nature, 611(7935), 380–386.
Mei, L., Reynolds, M. J., Garbett, D., Gong, R., Meyer, T., & Alushin, G. M. (2022). Structural mechanism for bidirectional actin cross-linking by T-plastin. Proceedings of the National Academy of Sciences of the United States of America, 119(37), e2205370119.
Gong, R., Jiang, F., Moreland, Z. G., Reynolds, M. J., de Los Reyes, S. E., Gurel, P., Shams, A., Heidings, J. B., Bowl, M. R., Bird, J. E., & Alushin, G. M. (2022). Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Science advances, 8(29), eabl4733.
Sun, X., & Alushin, G. M. (2022). Cellular force-sensing through actin filaments. The FEBS journal, 10.1111/febs.16568.
Moreland, Z. G., Jiang, F., Aguilar, C., Barzik, M., Gong, R., Shams, A., Faaborg-Andersen, C., Werth, J. C., Harley, R., Sutton, D. C., Cole, S. M., Parker, A., Morse, S., Wilson, E., Takagi, Y., Sellers, J. R., Brown, S. D. M., Friedman, T. B., Alushin, G. M., Bowl, M. R., & Bird, J. E. (2021). Myosin-driven Nucleation of Actin Filaments Drives Stereocilia Development Critical for Hearing. bioRxiv, 2021.2007.2009.451618.