Monday Lecture Series
(open to the Rockefeller community)
Monday, October 3, 2022
Michael P. Rout, Ph.D.
George and Ruby deStevens Professor,
Head of the Laboratory of Cellular and Structural Biology,
The Rockefeller University
A Tour of the Pore: Insights into the Architecture and Function Adaptations of the Nuclear Pore Complex
Recommended Readings:
Empirical Articles
Nudelman, I., Fernandez-Martinez, J., & Rout, M. P. (2022). Affinity Isolation of Endogenous Saccharomyces Cerevisiae Nuclear Pore Complexes. Methods in molecular biology, 2502, 3–34.
Akey, C. W., Singh, D., Ouch, C., Echeverria, I., Nudelman, I., Varberg, J. M., Yu, Z., Fang, F., Shi, Y., Wang, J., Salzberg, D., Song, K., Xu, C., Gumbart, J. C., Suslov, S., Unruh, J., Jaspersen, S. L., Chait, B. T., Sali, A., Fernandez-Martinez, J., Ludtke, S. J., Villa, E., & Rout, M. P. (2022). Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185(2), 361–378.e25.
Borah, S., Thaller, D. J., Hakhverdyan, Z., Rodriguez, E. C., Isenhour, A. W., Rout, M. P., King, M. C., & Lusk, C. P. (2021). Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state. Molecular biology of the cell, 32(15), 1359–1373.
Hakhverdyan, Z., Molloy, K. R., Keegan, S., Herricks, T., Lepore, D. M., Munson, M., Subbotin, R. I., Fenyö, D., Aitchison, J. D., Fernandez-Martinez, J., Chait, B. T., & Rout, M. P. (2021). Dissecting the Structural Dynamics of the Nuclear Pore Complex. Molecular cell, 81(1), 153–165.e7.
Dou, Y., Kalmykova, S., Pashkova, M., Oghbaie, M., Jiang, H., Molloy, K. R., Chait, B. T., Rout, M. P., Fenyö, D., Jensen, T. H., Altukhov, I., & LaCava, J. (2020). Affinity proteomic dissection of the human nuclear cap-binding complex interactome. Nucleic acids research, 48(18), 10456–10469.
Review Articles
Obado, S. O., Rout, M. P., & Field, M. C. (2022). Sending the message: specialized RNA export mechanisms in trypanosomes. Trends in parasitology, 38(10
