Webinar Friday Lecture Series
(open to the Tri-I community)
Friday, November 20, 2020
Kenya Honda, M.D., Ph.D.
Professor
Department of Microbiology and Immunology
Keio University
Mining the Microbiota for Rationally Designed Biotherapies
Recommended Readings:
Empirical Articles
Tanoue, Takeshi; Morita, Satoru; Plichta, Damian R.; et al. (2019). A defined commensal consortium elicits CD8 T cells and anti-cancer immunity. NATURE. 565 (7741): 600-605
Stein, Richard R.; Tanoue, Takeshi; Szabady, Rose L.; et al. (2018). Computer-guided design of optimal microbial consortia for immune system modulation. ELIFE. 7
Atarashi, Koji; Suda, Wataru; Luo, Chengwei; et al. (2017). Ectopic colonization of oral bacteria in the intestine drives T(H)1 cell induction and inflammation. SCIENCE. 358 (6361): 359-365
Chai, Jiani N.; Peng, Yangqing; Rengarajan, Sunaina; et al. (2017). Helicobacter species are potent drivers of colonic T cell responses in homeostasis and inflammation. SCIENCE IMMUNOLOGY. 2 (13)
Atarashi, Koji; Tanoue, Takeshi; Ando, Minoru; et al. (2015). Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells. CELL. 163 (2): 367-380
Atarashi, Koji; Tanoue, Takeshi; Oshima, Kenshiro; et al. (2013). T-reg induction by a rationally selected mixture of Clostridia strains from the human microbiota. NATURE. 500 (7461): 232-236
Atarashi, Koji; Tanoue, Takeshi; Shima, Tatsuichiro; et al. (2011). Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species. SCIENCE. 331 (6015): 337-341
Review Papers
Skelly, Ashwin N.; Sato, Yuko; Kearney, Sean; et al. (2019). Mining the microbiota for microbial and metabolite-based immunotherapies. NATURE REVIEWS IMMUNOLOGY. 19 (5): 305-323
Honda, Kenya; Littman, Dan R. (2016). The microbiota in adaptive immune homeostasis and disease. NATURE. 535 (7610): 75-84
Book Chapter
Honda, Kenya; Littman, Dan R. (2012). The Microbiome in Infectious Disease and Inflammation. ANNUAL REVIEW OF IMMUNOLOGY. 30: 759-795