Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, March 23, 2026
Michel Nussenzweig, M.D., Ph.D.
Senior Physician, Zanvil A. Cohn and Ralph M. Steinman Professor and Head of the Laboratory of Molecular Immunology; Investigator, Howard Hughes Medical Institute
How the Immune System Maintains Antibody Diversity While Developing High Affinity Responses
Recommended Readings:
Hartweger, Harald, et al. “B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing.” bioRxiv (2026): 2026-01.
Schaefer-Babajew, Dennis, et al. “Antibody Mediated Diversification of Primary and Secondary Immune Responses.” bioRxiv (2025): 2025-12.
Pyo, Andrew GT, et al. “Modeling the Synergetic Dynamics of B cells and TFH cells in Germinal Center Reactions.” bioRxiv (2025): 2025-11.
Merkenschlager, Julia, et al. “Regulated somatic hypermutation enhances antibody affinity maturation.” Nature 641.8062 (2025): 495-502.
MacLean, Andrew J., et al. “Affinity maturation of antibody responses is mediated by differential plasma cell proliferation.” Science 387.6732 (2025): 413-420.
