Evnin Chemical & Structural Biology Seminar Series
(open to the Rockefeller and Tri-Institutional communities)
Tuesday, October 27, 2026
James Fraser, Ph.D.
Department Chair and Professor, Bioengineering, University of California, San Francisco
Statistical Structural Biology
Recommended Readings:
Xu, Xinyu, et al. “Development of a random background to understand ligand optimization.” Nature (2026): 1-9.
Orta, Anna Karen, et al. “Structural Plasticity and Ligand Promiscuity of CYP3A4 Revealed by Cryo-EM.” Biorxiv: the Preprint Server for Biology (2026).
MacDermott-Opeskin, Hugo, et al. “Operational insights from the front lines of OpenADMET: lessons from our blind challenges.” (2026).
Fraser, James S., et al. “Mapping the avoid-ome: a systematic open-science approach to predictive ADMET.” Nature Communications 17.1 (2026): 4644.
Flowers, Jessica, et al. “Expanding automated multiconformer ligand modeling to macrocycles and fragments.” Elife 14 (2025): RP103797.
