(open to the Rockefeller and Tri-Institutional communities)
Friday, March 13, 2026
Leonard Zon, M.D.
Director of the Stem Cell Program, Boston Children’s Hospital; Grousbeck Professor of Pediatric Medicine, Harvard Medical School; Professor of Stem Cell and Regenerative Biology, Harvard University; Investigator, Howard Hughes Medical Institute
Stem Cell Clonality and the Niche
The Bruce Merrifield Distinguished Lecture
Recommended Readings:
Baron, Chloé S., et al. “Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis.” bioRxiv (2024): 2024-09.
Hagedorn, Elliott J., et al. “Transcription factor induction of vascular blood stem cell niches in vivo.” Developmental cell 58.12 (2023): 1037-1051.
Wattrus, Samuel J., and Leonard I. Zon. “Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish.” Blood advances 2.21 (2018): 3063-3069.
Perlin, Julie R., Audrey Sporrij, and Leonard I. Zon. “Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment.” Journal of molecular medicine 95.8 (2017): 809-819.
Dooley, Kimberly, and Leonard I. Zon. “Zebrafish: a model system for the study of human disease.” Current opinion in genetics & development 10.3 (2000): 252-256.
