Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, December 8, 2025
Ali Brivanlou, Ph.D.
Robert and Harriet Heilbrunn Professor and Head of the Laboratory of Synthetic Embryology, The Rockefeller University
Self-Organization and Symmetry Breaking in Human Embryo and Models
Recommended Readings:
De Santis, Riccardo, et al. “Crosstalk between tissue mechanics and BMP4 signaling regulates symmetry breaking in human gastrula models.” Cell Stem Cell 32.11 (2025): 1691-1704.
De Santis, Riccardo, et al. “The emergence of human gastrulation upon in vitro attachment.” Stem Cell Reports 19.1 (2024): 41-53.
Simunovic, Mijo, Eric D. Siggia, and Ali H. Brivanlou. “In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells.” Cell stem cell 29.6 (2022): 962-972.
Valet, Manon, Eric D. Siggia, and Ali H. Brivanlou. “Mechanical regulation of early vertebrate embryogenesis.” Nature Reviews Molecular Cell Biology 23.3 (2022): 169-184.
Brivanlou, Ali H., Nicolas Rivron, and Norbert Gleicher. “How will our understanding of human development evolve over the next 10 years.” Nature Communications 12.1 (2021): 4614.
