Friday Lecture Series
(open to the Rockefeller and Tri-Institutional communities)
Friday, February 14, 2025
Jason Chin, Ph.D.
Professor of Chemistry & Chemical Biology, Department of Chemistry, University of Cambridge; Programme Leader, Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology
Reprogramming the Genetic Code
Recommended Readings:
Tian, Rongzhen, et al. “Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli.” Science 383.6681 (2024): 421-426.
Dunkelmann, Daniel L., et al. “Adding α, α-disubstituted and β-linked monomers to the genetic code of an organism.” Nature 625.7995 (2024): 603-610.
Robertson, Wesley E., et al. “Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS.” Nature Protocols 16.5 (2021): 2345-2380.
Fredens, Julius, et al. “Total synthesis of Escherichia coli with a recoded genome.” Nature 569.7757 (2019): 514-518.
Liu, Chang C., et al. “Toward an orthogonal central dogma.” Nature Chemical Biology 14.2 (2018): 103-106.