Friday Lecture Series
(open to the Rockefeller and Tri-Institutional communities)
Friday, February 6, 2026
David Julius, Ph.D.
Morris Herzstein Chair in Molecular Biology and Medicine, Professor, Department of Physiology, University of California, San Francisco
Structural Energetics of Cold Sensitivity
The William H. Stein Memorial Lecture
Recommended Readings:
Choi, Kevin Y., et al. “The structural basis of cold sensitivity.” bioRxiv (2025): 2025-06.
Julius, David. “TRP channels and pain.” Annual review of cell and developmental biology 29.1 (2013): 355-384.
Myers, Benjamin R., Yaron M. Sigal, and David Julius. “Evolution of thermal response properties in a cold-activated TRP channel.” PloS one 4.5 (2009): e5741.
Bautista, Diana M., et al. “The menthol receptor TRPM8 is the principal detector of environmental cold.” Nature 448.7150 (2007): 204-208.
McKemy, David D., Werner M. Neuhausser, and David Julius. “Identification of a cold receptor reveals a general role for TRP channels in thermosensation.” Nature 416.6876 (2002): 52-58.