Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, September 29, 2025
Sohail Tavazoie, M.D., Ph.D.
Leon Hess Professor, Senior Attending Physician, and Head of the Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology, The Rockefeller University
Metastasis as a Heritable Disease Shaped by our Infectious Evolutionary History and Nervous System
Recommended Readings:
Chen, Siyu, et al. “Discovery of a tRNA-regulatory transcription factor that suppresses breast cancer metastasis.” bioRxiv (2025): 2025-04.
Ronnacker, Julian, et al. “Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia.” Blood (2025).
Mei, Wenbin, et al. “A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor.” Cell 188.2 (2025): 371-389.
Adaku, Nneoma, et al. “Apolipoprotein E2 stimulates protein synthesis and promotes melanoma progression and metastasis.” Cancer research 83.18 (2023): 3013-3025.
Nguyen, Alexander, et al. “Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness.” Nature communications 7.1 (2016): 11246.