Chemical & Structural Biology Seminar Series
(open to the Rockefeller and Tri-Institutional communities)
Wednesday, April 30, 2025
Yael David, Ph.D.
Associate Member, Chemical Biology Program, Memorial Sloan Kettering Cancer Center
Leveraging Chemical Biology to Uncover Epigenetic Mechanisms in Disease
Recommended Readings:
Prescott, Nicholas A., et al. “A nucleosome switch primes Hepatitis B Virus infection.” Cell (2025).
Zheng, Qingfei, et al. “Bidirectional histone monoaminylation dynamics regulate neural rhythmicity.” Nature (2025): 1-9.
Agustinus, Albert S., and Yael David. “Thinking outside the chromosome: epigenetic mechanisms in non-canonical chromatin species.” Nature structural & molecular biology 31.1 (2024): 8-10.
Agustinus, Albert S., et al. “Epigenetic dysregulation from chromosomal transit in micronuclei.” Nature 619.7968 (2023): 176-183.
Zheng, Qingfei, et al. “Non-enzymatic covalent modifications: a new link between metabolism and epigenetics.” Protein & cell 11.6 (2020): 401-416.
Zheng, Qingfei, et al. “Reversible histone glycation is associated with disease-related changes in chromatin architecture.” Nature Communications 10.1 (2019): 1289.
