Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, January 27, 2025
Elizabeth Campbell, Ph.D.
Corinne P. Greenberg Women & Science Professor and Head of the Laboratory of Molecular Pathogenesis, The Rockefeller University
Targeting Multiple Steps of the Transcription Cycle Combats Resistance And Potentiates Rifampicin Activity in Mycobacterium Tuberculosis infected Granulomas
Recommended Readings:
Eckartt, Kathryn A., et al. “Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis.” Nature 628.8006 (2024): 186-194.
Ju, Xiangwu, et al. “Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome.” Nature 627.8003 (2024): 424-430.
Dheda, Keertan, et al. “Multidrug-resistant tuberculosis.” Nature Reviews Disease Primers 10.1 (2024): 22.
Chen, James, Hande Boyaci, and Elizabeth A. Campbell. “Diverse and unified mechanisms of transcription initiation in bacteria.” Nature Reviews Microbiology 19.2 (2021): 95-109.
Lilic, Mirjana, et al. “The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.” Proceedings of the National Academy of Sciences 117.48 (2020): 30423-30432.
