Hybrid Monday Lecture Series
(open to the Rockefeller community)
Monday, November 11, 2024
Roderick MacKinnon, M.D.
John D. Rockefeller Jr. Professor and Head of the Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University; Investigator, Howard Hughes Medical Institute
Higher Order Transient (HOT) Structures and the Principle of Dynamic Connectivity in Membrane Signaling
Recommended Readings:
Fu, Ziao, and Roderick MacKinnon. “Structure of the flotillin complex in a native membrane environment.” Proceedings of the National Academy of Sciences 121.29 (2024): e2409334121.
Falzone, Maria E., and Roderick MacKinnon. “The mechanism of Gαq regulation of PLCβ3-catalyzed PIP2 hydrolysis.” Proceedings of the National Academy of Sciences 120.48 (2023): e2315011120.
Tao, Xiao, Chen Zhao, and Roderick MacKinnon. “Membrane protein isolation and structure determination in cell-derived membrane vesicles.” Proceedings of the National Academy of Sciences 120.18 (2023): e2302325120.
Nair, Arathi, et al. “Conceptual evolution of cell signaling.” International journal of molecular sciences 20.13 (2019): 3292.
Gouaux, Eric, and Roderick MacKinnon. “Principles of selective ion transport in channels and pumps.” Science 310.5753 (2005): 1461-1465.
